Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.MACROPHAGE INFLAMMATORY PROTEIN 1 ALPHA (MIP-1a) AFFINITY PURIFIED Antibody
Purified Sheep Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E, DB |
|---|---|
| Host | Sheep |
| Clonality | Polyclonal |
| Other Names | MIP-1-alpha; Macrophage inflammatory protein 1-alpha; C-C motif chemokine 3; Small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; G0/G1 switch regulatory protein 19-1; G0S19-1 protein; SIS-beta; PAT 464.1; CCL3; G0S19-1; MIP1A; SCYA4 |
|---|---|
| Reconstitution & Storage | Store at -20°C. Avoid freeze / thaw cycles. Short term storage +2°C-+8°C |
| Precautions | MACROPHAGE INFLAMMATORY PROTEIN 1 ALPHA (MIP-1a) AFFINITY PURIFIED Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
MIP-1α is a member of the CC chemokine family of proteins which have been shown to be produced by numerous cell types including activated T cells, B cells, monocytes, mast cells and endothelial cells. MIP-1α acts as a monocyte chemoattractant and has been shown to act as a stem cell inhibitory factor. RANDOX recombinant MIP-1α comprises a 68 amino acid fragment (27-92) mature MIP-1? protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
References
Menten, P. et al., (2002) Cytokine Growth Factor Rev. 13 (6) : 455-481.
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