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Purified Sheep Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E, DB |
|---|---|
| Host | Sheep |
| Clonality | Polyclonal |
| Other Names | Enolase 2; Neuronal specific enolase; EC. 4.2.1.11; 2-phospho-Dglycerate hydrolyase; enolase 2 (gamma neuronal); neuron specific enolase; neural enolase |
|---|---|
| Reconstitution & Storage | Store at -20°C. Avoid freeze / thaw cycles. Short term storage +2°C-+8°C |
| Precautions | NEURONAL SPECIFIC ENOLASE (NSE) Affinity Purified Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NSE is the isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells . NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival. RANDOX recombinant NSE comprises a 433 amino acid fragment (2-434) corresponding to processed mature NSE protein and is expressed in E. coli with an aminoterminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
References
Kaiser, E. et al.,(1989) Clin. Chim. Acta. 183 (1) :13-4
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