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CLPH Antibody

  • WB - CLPH Antibody ASC11021
    Western blot analysis of CLPH in human testis tissue lysate with CLPH antibody at 1 µg/mL.
  • IHC - CLPH Antibody ASC11021
    Immunohistochemistry of CLPH in human testis tissue with CLPH antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96KC9
Other Accession NP_149113, 90652863
Reactivity Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Application Notes CLPH antibody can be used for detection of CLPH by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Additional Information
Gene ID 85438
Target/Specificity C4orf35;
Reconstitution & Storage CLPH antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsCLPH Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CABS1
Synonyms C4orf35
Cellular Location Cytoplasm. Mitochondrion. Cell projection, cilium, flagellum Note=Detected in mitochondria of step 17 to 18 spermatids Associated with the mitochondrial inner membrane in step 18 spermatids (By similarity). EMBL; AF380838; AAK57455.1; -; mRNA EMBL; AK057459; BAB71497.1; -; mRNA EMBL; AK315022; BAG37512.1; -; mRNA EMBL; AC106884; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471057; EAX05615.1; -; Genomic_DNA EMBL; BC046111; AAH46111.1; -; mRNA CCDS; CCDS3539.1; - RefSeq; NP_149113.3; NM_033122.3 UniGene; Hs.120316; - ProteinModelPortal; Q96KC9; - BioGrid; 124525; 9 STRING; 9606.ENSP00000273936; - PhosphoSitePlus; Q96KC9; - BioMuta; CABS1; - DMDM; 317373451; - PaxDb; Q96KC9; - PeptideAtlas; Q96KC9; - PRIDE; Q96KC9; - ProteomicsDB; 77060; - DNASU; 85438; - Ensembl; ENST00000273936; ENSP00000273936; ENSG00000145309 GeneID; 85438; - KEGG; hsa:85438; - UCSC; uc003hff.4; human CTD; 85438; - DisGeNET; 85438; - EuPathDB; HostDB:ENSG00000145309.5; - GeneCards; CABS1; - HGNC; HGNC:30710; CABS1 HPA; HPA044016; - HPA; HPA055352; - neXtProt; NX_Q96KC9; - OpenTargets; ENSG00000145309; - PharmGKB; PA162379775; - eggNOG; ENOG410INTR; Eukaryota eggNOG; ENOG4111EGF; LUCA GeneTree; ENSGT00390000015647; - InParanoid; Q96KC9; - OMA; KIYSHPP; - OrthoDB; EOG091G0FBE; - PhylomeDB; Q96KC9; - TreeFam; TF338174; - GenomeRNAi; 85438; - PRO; PR:Q96KC9; - Proteomes; UP000005640; Chromosome 4 Bgee; ENSG00000145309; - CleanEx; HS_C4orf35; - Genevisible; Q96KC9; HS GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central GO; GO:0031514; C:motile cilium; ISS:UniProtKB GO; GO:0005509; F:calcium ion binding; ISS:UniProtKB GO; GO:0007283; P:spermatogenesis; IBA:GO_Central InterPro; IPR026118; Ca-bd_spermatid PANTHER; PTHR22810; PTHR22810; 3 Pfam; PF15367; CABS1; 1 2: Evidence at transcript level; Calcium; Cell projection; Cilium; Complete proteome; Cytoplasm; Flagellum; Mitochondrion; Phosphoprotein; Polymorphism; Reference proteome CHAIN 1 395 Calcium-binding and spermatid-specific protein 1 /FTId=PRO_0000339178 MOD_RES 273 273 Phosphoserine {ECO:0000250|UniProtKB:Q68FX6} MOD_RES 287 287 Phosphothreonine; by CK2 {ECO:0000250|UniProtKB:Q68FX6} MOD_RES 319 319 Phosphoserine {ECO:0000250|UniProtKB:Q68FX6} MOD_RES 376 376 Phosphoserine {ECO:0000250|UniProtKB:Q68FX6} VARIANT 76 76 K -> Q (in dbSNP:rs3796706) /FTId=VAR_043924 VARIANT 211 211 T -> I (in dbSNP:rs1351419) {ECO:0000269|PubMed:14702039, ECO:0000269|PubMed:15489334, ECO:0000269|Ref.4} /FTId=VAR_043925 VARIANT 298 298 W -> G (in dbSNP:rs2291182) /FTId=VAR_043926 SEQUENCE 395 AA; 43003 MW; 92165DC845F00BBB CRC64; MAEDGLPKIY SHPPTESSKT PTAATIFFGA DNAIPKSETT ITSEGDHVTS VNEYMLESDF STTTDNKLTA KKEKLKSEDD MGTDFIKSTT HLQKEITSLT GTTNSITRDS ITEHFMPVKI GNISSPVTTV SLIDFSTDIA KEDILLATID TGDAEISITS EVSGTLKDSS AGVADAPAFP RKKDEADMSN YNSSIKSNVP ADEAVQVTDS TIPEAEIPPA PEESFTTIPD ITALEEEKIT EIDLSVLEDD TSAVATLTDS DEKFITVFEL TTSAEKDKDK REDTLLTDEE TTEGASIWME RDTANEAETH SVLLTAVESR YDFVVPASIA TNLVEESSTE EDLSETDNTE TVPKITEPFS GTTSVLDTPD YKEDTSTTET DIFELLKEEP DEFMI
Research Areas
Citations (0)

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CLPH Antibody: CLPH (Casein-Like phosphoprotein) is a recently discovered, evolutionarily conserved, testis-specific cytoplasmic protein expressed exclusively in postmeiotic germ cells in rat spermatogenesis. CLPH is a novel casein kinase 2-phosphorylated disordered and calcium-binding protein that displays strong variation in relative expression levels during spermatogenesis. It is frequently associated with the mitochondrial inner membrane during the last steps of spermatid differentiation and is involved in the extremely complex structural rearrangements occurring in haploid germ cells during spermiogenesis.


Calvel P, Kervarrec C, Lavigne R, et al. CLPH, a novel casein kinase 2-phosphorylated disordered protein, is specifically associated with postmeiotic germ cells in rat spermatogenesis. J. Proteome Res.2009; 8:2953-65.

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$ 335.00
Cat# ASC11021
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