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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CaBP7 Antibody   

CaBP7 Antibody

  • WB - CaBP7 Antibody ASC11173
    Western blot analysis of CaBP7 in Hela cell lysate with CaBP7 antibody at (A) 1 and (B) 2 µg/mL.
  • ICC - CaBP7 Antibody ASC11173
    Immunocytochemistry of CaBP7 in HeLa cells with CaBP7 antibody at 4 µg/mL.
  • IF - CaBP7 Antibody ASC11173
    Immunofluorescence of CABP7 in HeLa cells with CAPB7 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86V35
Other Accession NP_872333, 32698884
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 24453 Da
Application Notes CaBP7 antibody can be used for detection of CaBP7 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunocytochemistry starting at 4 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 164633
Target/Specificity CABP7;
Reconstitution & Storage CaBP7 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsCaBP7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CABP7
Synonyms CALN2
Function Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Cytoplasm, perinuclear region. Cell membrane; Single-pass type IV membrane protein
Research Areas
Citations (0)

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CaBP7 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.


Sokal I, Li N, Verlinde CL, et al. Ca2+-binding proteins in the retina: from discovery to etiology of human disease. Biochim. Biophys. Acta.2000; 1498: 233-51.
Haeseleer F, Imanishi Y, Sokal I, et al. Calcium-binding proteins: intracellular sensors from the calmodulin superfamily. Biochem. Biophys. Res. Commun.2002; 290:615-23.
Ikura M, Osawa M, and Ames JB. The role of calcium-binding proteins in the control of transcription: structure to function. Bioessays2002; 24:625-36.
McCue HV, Burgoyne RD, Haynes LP. Membrane targeting of the EF-hand containing calcium-sensing proteins CaBP7 and CaBP8. Biochem. Biophys. Res. Commun.2009; 380:825-31.

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$ 335.00
Cat# ASC11173
Availability: 5-7days
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