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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ZIMP7 Antibody   

ZIMP7 Antibody

  • WB - ZIMP7 Antibody ASC11300
    Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 µg/ml and (B) 0.5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NF64
Other Accession Q8NF64, 54607108
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 96537 Da
Application Notes ZIMP7 antibody can be used for detection of ZIMP7 by Western blot at 0.25 - 0.5 µg/mL.
Additional Information
Gene ID 83637
Target/Specificity ZMIZ2; At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
Reconstitution & Storage ZIMP7 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsZIMP7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZMIZ2
Synonyms KIAA1886, ZIMP7
Function Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.
Cellular Location Nucleus. Note=Detected at replication foci throughout S phase
Tissue Location Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary
Research Areas
Citations (0)

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ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.


Huang CY, Beliakoff J, Li X, et al. hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes. Mol. Endocrinol. 2005; 19:2915-29
Ueki N, Oda T, Kondo M, et al. Selection system for genes encoding nuclear-targeted proteins. Nat. Biotechnol. 1998; 16:1338-42.
Beliakoff J and Sun Z. Zimp7 and Zimp10, two novel PIAS-like proteins, function as androgen receptor coregulators. Nucl. Recept. Signal. 2006; 4:e017
Peng Y, Lee J, Zhu C, et al. A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcription. J. Biol. Chem. 2010; 285:11465-75.

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$ 335.00
Cat# ASC11300
Availability: 5-7days
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