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HDGFRP2 Antibody

  • WB - HDGFRP2 Antibody ASC11351
    Western blot analysis of HDGFRP2 in rat lung tissue lysate with HDGFRP2 antibody at 2 µg/mL .
  • IHC - HDGFRP2 Antibody ASC11351
    Immunohistochemistry of HDGFRP2 in rat liver tissue with HDGFRP2 antibody at 5 µg/mL.
  • IF - HDGFRP2 Antibody ASC11351
    Immunofluorescence of HDGFRP2 in rat liver tissue with HDGFRP2 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z4V5
Other Accession EAW69215, 48255931
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 74317 Da
Application Notes HDGFRP2 antibody can be used for detection of HDGFRP2 by Western blot at 0.5 - 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 84717
Target/Specificity HDGFRP2; At least two isoforms of HDGFRP2 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other HDGFRP family members
Reconstitution & Storage HDGFRP2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsHDGFRP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HDGFL2 (HGNC:14680)
Function Involved in cellular growth control, through the regulation of cyclin D1 expression.
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q3UMU9}.
Tissue Location Widely expressed. High expression is found in heart, skeletal muscle, ovary and testis. Overexpression is frequently observed in hepatocellular carcinoma samples
Research Areas
Citations (0)

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HDGFRP2 Antibody: Hepatoma-derived growth factor-related protein 2 (HDGFRP2) is a widely expressed member of protein family that contains the HDGF related proteins 1-4 and lens epithelial derived growth factor (LEDGF). These family members show extensive homology at the amino terminus (termed the hath region). Little is known of the role of HDGFRP2, but like the related LEDGF, HDGFRP2 can bind HIV-1 integrase and stimulate HIV-1 integrase activity in vitro.


El-Tahir HM, Dietz F, Dringen R, et al. Expression of Hepatoma-derived growth factor family members in the adult central nervous system. BMC Neurosci. 2006; 7:6.
Izumoto Y, Kuroda T, Harada H, et al. Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus. Biochem. Biophys. Res. Commun. 1997; 238:26-32
Cherepanov P, Devroe E, Silver PA, et al. Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. J. Biol. Chem. 2004; 279:48883-92.

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$ 335.00
Cat# ASC11351
Availability: 5-7days
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