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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EIG121 Antibody   

EIG121 Antibody

  • WB - EIG121 Antibody ASC11360
    Western blot analysis of EIG121 in MCF7 cell lysate with EIG121 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • ICC - EIG121 Antibody ASC11360
    Immunocytochemistry of EIG121 in MCF7 cells with EIG121 antibody at 5 µg/mL.
  • IF - EIG121 Antibody ASC11360
    Immunofluorescence of EIG121 in MCF7 cells with EIG121 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6UXG2
Other Accession NP_065826, 38569482
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 111382 Da
Application Notes EIG121 antibody can be used for detection of EIG121 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 1957
Target/Specificity EGI; At least four isoforms of EIG121 known to exist. EIG121 antibody is predicted to not cross-react with other UPF0577 protein family members.
Reconstitution & Storage EIG121 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsEIG121 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIAA1324
Synonyms EIG121
Function May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway.
Cellular Location Cell membrane; Single-pass type I membrane protein Late endosome membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass membrane protein
Tissue Location Expressed in normal endometrium but overexpressed in endometroid tumors
Research Areas
Citations (0)

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EIG121 Antibody: EIG121 (Estrogen-induced gene 121 protein) is thought to play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma. It belongs to the UPF0577 family. It is a 1013 amino acid single-pass transmembrane protein that, though expressed in normal endometrium, is overexpressed in endometriod tumors. As an evolutionarily conserved gene, EIG121 is also expressed during early xenopus development, showing maximum expression at the gastrula stage.


Deng L, Broaddus RR, McCampbell A, et al. Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer. Clin. Cancer Res. 2005; 11:8258-64.
Deng L, Feng J, Broaddus RR. The novel estrogen-induced gene EIG121 regulates autophagy and promotes cell survival under stress. Cell Death Dis. 2010; 1:e32.
Araki T, Kusakabe M and Nishida E. Expression of estrogen induced gene 121-like (EIG121L) during early Xenopus development. Gene Expr. Patterns 2007; 7:666-71.

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$ 335.00
Cat# ASC11360
Availability: 5-7days
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