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SPATA6 Antibody

  • WB - SPATA6 Antibody ASC11396
    Western blot analysis of SPATA6 in A20 cell lysate with SPATA6 antibody at 1 µg/mL.
  • IHC - SPATA6 Antibody ASC11396
    Immunohistochemistry of SPATA6 in mouse testis tissue with SPATA6 antibody at 2.5 µg/mL.
  • IF - SPATA6 Antibody ASC11396
    Immunofluorescence of SPATA6 in mouse testis tissue with SPATA6 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NWH7
Other Accession NP_061946, 9506603
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 55989 Da
Application Notes SPATA6 antibody can be used for detection of SPATA6 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 54558
Target/Specificity SPATA6; At least three isoforms of SPATA6 are known to exist; this antibody will detect only the longest two isoforms. SPATA6 antibody is predicted to not cross-react with other SPATA protein family members.
Reconstitution & Storage SPATA6 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSPATA6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits.
Cellular Location Secreted {ECO:0000250|UniProtKB:Q3U6K5}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q3U6K5} Note=Specifically localizes to the segmented columns and the capitulum of the sperm connecting piece {ECO:0000250|UniProtKB:Q3U6K5}
Research Areas
Citations (0)

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SPATA6 Antibody: The development of spermatogonial stem cells into spermatozoa, i.e., spermatogenesis, is a highly ordered process that requires multiple proteins, including some that are testis-specific or testis-specific isoforms of genes that are expressed in other tissues. One such protein is SPATA6: while its full-length isoform is expressed in multiple tissues including thymus, brain and testis, the shorter isoform is expressed only in testis. It has some homology to the motor domain of kinesin related proteins and with the C. elegans neural calcium sensor protein NCS-2.


Venables JP. Alternative splicing in the testes. Curr. Opin. Genet. Dev. 2002; 12:615-9.
Oh C, Aho H, Shamsadin R, et al. Characterization, expression pattern and chromosomal localization of the spermatogenesis associated 6 gene (Spata6). Mol. Human Reprod. 2003; 9:321-30.

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$ 335.00
Cat# ASC11396
Availability: 5-7days
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