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Thymopoietin Antibody

  • WB - Thymopoietin Antibody ASC11407
    Western blot analysis of Thymopoietin in HeLa cell lysate with Thymopoietin antibody at 0.25 µg/mLl in (A) the absence and (B) the presence of blocking peptide.
  • ICC - Thymopoietin Antibody ASC11407
    Immunocytochemistry of Thymopoietin in HeLa cells with Thymopoietin antibody at 2.5 µg/mL.
  • IF - Thymopoietin Antibody ASC11407
    Immunofluorescence of Thymopoietin in HeLa cells with Thymopoietin antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P42166
Other Accession NP_003267, 4507555
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 75492 Da
Application Notes Thymopoietin antibody can be used for detection of Thymopoietin by Western blot at 0.25 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 5 µg/mL.
Additional Information
Gene ID 7112
Target/Specificity TMPO; At least three isoforms of Thymopoietin are known to exist; this antibody will detect all isoforms. Thymopoietin antibody is predicted to not cross-react with other LEM domain-containing proteins.
Reconstitution & Storage Thymopoietin antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsThymopoietin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LAP2
Function May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.
Cellular Location Nucleus. Chromosome. Note=Expressed diffusely throughout the nucleus
Tissue Location Expressed in many tissues. Most abundant in adult thymus and fetal liver
Research Areas
Citations (0)

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Thymopoietin Antibody: Thymopoietin (TMPO), also known as LAP2, is a widely expressed lem-domain-containing nuclear protein that is thought to play an important role in the regulation of nuclear architecture by binding lamin B1 and chromosomes in a manner regulated by phosphorylation during mitosis. Thymopoietin associates with nucleoplasmic lamins A/C, which are encoded by the dilated cardiomyopathy (DCM) gene LMNA; mutations in Thymopoietin disrupt this binding, suggesting that Thymopoietin may be a candidate disease gene for DCM.


Harris CA, Andryuk PJ, Cline SW, et al. Structure and mapping of the human thymopoietin (TMPO) gene and relationship of human TMPO beta to rat lamin-associated polypeptide 2. Genomics 1995; 28:198-205.
Taylor MR, Slavov D, Gajewski A, et al. Thymopoietin (lamina-associated polypeptide 2) gene mutation associated with dilated cardiomyopathy. Hum. Mutat. 2005; 26:566-

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$ 335.00
Cat# ASC11407
Availability: 5-7days
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