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>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   SPATA19 Antibody   

SPATA19 Antibody

  • WB - SPATA19 Antibody ASC11413
    Western blot analysis of SPATA19 in rat lung tissue lysate with SPATA19 antibody at (A) 1 and (B) 2 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z5L4
Other Accession EAW67810, 28376652
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Isotype IgY
Application Notes SPATA19 antibody can be used for detection of SPATA19 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 219938
Target/Specificity SPATA19; At least two isoforms of SPATA19 are known to exist; this antibody will detect both isoforms. SPATA19 antibody is predicted to not cross-react with other SPATA family members.
Reconstitution & Storage SPATA19 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSPATA19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPATA19
Synonyms SPERGEN1
Function May have a role in spermiogenesis.
Cellular Location Mitochondrion outer membrane.
Tissue Location Expressed specifically in testis. EMBL; AF521713; AAP80739.1; -; mRNA EMBL; AK098717; BAC05390.1; -; mRNA EMBL; BC058039; AAH58039.1; -; mRNA CCDS; CCDS8493.1; - RefSeq; NP_001278921.1; NM_001291992.1 RefSeq; NP_777587.1; NM_174927.2 UniGene; Hs.97541; - ProteinModelPortal; Q7Z5L4; - SMR; Q7Z5L4; - BioGrid; 128597; 5 STRING; 9606.ENSP00000299140; - iPTMnet; Q7Z5L4; - PhosphoSitePlus; Q7Z5L4; - BioMuta; SPATA19; - EPD; Q7Z5L4; - PaxDb; Q7Z5L4; - PeptideAtlas; Q7Z5L4; - PRIDE; Q7Z5L4; - ProteomicsDB; 69320; - DNASU; 219938; - Ensembl; ENST00000299140; ENSP00000299140; ENSG00000166118 Ensembl; ENST00000532889; ENSP00000435248; ENSG00000166118 GeneID; 219938; - KEGG; hsa:219938; - UCSC; uc001qgv.2; human CTD; 219938; - DisGeNET; 219938; - EuPathDB; HostDB:ENSG00000166118.7; - GeneCards; SPATA19; - HGNC; HGNC:30614; SPATA19 HPA; HPA040082; - MIM; 609805; gene neXtProt; NX_Q7Z5L4; - OpenTargets; ENSG00000166118; - PharmGKB; PA142670884; - eggNOG; ENOG410IX9F; Eukaryota eggNOG; ENOG4111CPH; LUCA GeneTree; ENSGT00390000002749; - HOGENOM; HOG000154400; - HOVERGEN; HBG093991; - InParanoid; Q7Z5L4; - OMA; QHWLKKT; - OrthoDB; EOG091G0TH2; - PhylomeDB; Q7Z5L4; - TreeFam; TF337965; - GenomeRNAi; 219938; - PRO; PR:Q7Z5L4; - Proteomes; UP000005640; Chromosome 11 Bgee; ENSG00000166118; - CleanEx; HS_SPATA19; - ExpressionAtlas; Q7Z5L4; baseline and differential Genevisible; Q7Z5L4; HS GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW GO; GO:0007275; P:multicellular organism development; IEA:UniProtKB-KW GO; GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW InterPro; IPR028219; SPATA19 PANTHER; PTHR36468; PTHR36468; 2 Pfam; PF15212; SPATA19; 2 2: Evidence at transcript level; Complete proteome; Developmental protein; Differentiation; Membrane; Mitochondrion; Mitochondrion outer membrane; Phosphoprotein; Polymorphism; Reference proteome; Spermatogenesis; Transit peptide TRANSIT 1 24 Mitochondrion. CHAIN 25 167 Spermatogenesis-associated protein 19, mitochondrial /FTId=PRO_0000251609 MOD_RES 26 26 Phosphoserine {ECO:0000250|UniProtKB:Q920Q3} MOD_RES 129 129 Phosphoserine {ECO:0000250|UniProtKB:Q920Q3} VARIANT 50 50 A -> V (in dbSNP:rs2282602) /FTId=VAR_027697 SEQUENCE 167 AA; 19186 MW; 4FBEFCD966887FEB CRC64; MIITTWIVYI LARKGVGLPF LPITSSDIDV VESEAVSVLH HWLKKTEEEA SRGIKEKLSI NHPSQGVREK MSTDSPPTHG QDIHVTRDVV KHHLSKSDLL ANQSQEVLEE RTRIQFIRWS HTRIFQVPSE MTEDIMRDRI EQVRRSISRL TDVSAQDFSM RPSSSDC
Research Areas
Citations (0)

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SPATA19 Antibody: SPATA19, also known as SPERGEN1, was initially identified as a testis-specific protein that localizes to the surface of mitochondria in the middle piece of mature spermatozoa. Recent experiments have shown that elevated levels of SPATA19 have been found in basal cell carcinomas and prostate cancers, suggesting that SPATA19 may serve as a putative cancer biomarker and a target for cancer immunotherapy.


Miyamoto T, Sengoku K, Hasuike S, et al. Isolation and expression analysis of the human testis-specific gene, SPERGEN-1, a spermatogenic cell-specific gene-1. J. Assist. Reprod. Genet. 2003; 20:101-4.
Doiguchi M, Mori T, Toshimori K, et al. Spergen-1 might be an adhesive molecule associated with mitochondria in the middle piece of spermatozoa. Dev. Biol. 2002; 252:127-37.
Ghafouri-Fard S, Abbasi A, Moslehi H, et al. Elevated levels of testis-specific genes TEX101 and SPATA19 in basal cell carcinoma and their correlation with clinical and pathological features. Br. J. Dermatol. 2010; 162:772-9
Ghafouri-Fard S, Ousati Ashtiani Z, Sabah Golian B, et al. Expression of two testis-specific genes, SPATA19 and LEMD1, in prostate cancer. Arch. Med. Res. 2010; 41:195-200.

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$ 335.00
Cat# ASC11413
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