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DDX41 Antibody

  • WB - DDX41 Antibody ASC11657
    Western blot analysis of DDX41 in rat brain tissue lysate with DDX41 antibody at 1 µg/mL.
  • IHC - DDX41 Antibody ASC11657
    Immunohistochemistry of DDX41 in rat brain tissue with DDX41 antibody at 2.5 µg/ml.
  • IF - DDX41 Antibody ASC11657
    Immunofluorescence of DDX41 in rat brain tissue with DDX41 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UJV9
Other Accession NP_057306, 21071032
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 68 kDa

Observed: 70 kDa
Application Notes DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 51428
Target/Specificity DDX41; At least two isoforms of DDX41 are known to exist; this antibody will detect both isoforms.
Reconstitution & Storage DDX41 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsDDX41 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DDX41
Synonyms ABS
Function Probable ATP-dependent RNA helicase. Is required during post-transcriptional gene expression. May be involved in pre-mRNA splicing.
Cellular Location Nucleus.
Citations (0)

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DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.


Cordin O, Banroques J, Tanner NK, et al. The DEAD-box protein family of RNA helicases. Gene 2006; 367:17-37.
Linder P. Dead-box proteins: a family affair—active and passive players in RNP-remodeling. Nucleic Acids Res. 2006; 34:4168-80.
Abdul-Ghani M, Hartman KL, and Ngsee JK. Abstrakt interacts with and regulates the expression of sorting nexin-2. J. Cell Physiol. 2005; 204:210-8.
Zhang Z, Yuan B, Bao M, et al. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nat. Immunol. 2011; 12:959-65.

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$ 335.00
Cat# ASC11657
Availability: 5-7days
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