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KHDC1 Antibody

  • WB - KHDC1 Antibody ASC11678
    Western blot analysis of KHDC1 in rat liver tissue lysate with KHDC1 antibody at (A) 0.5 and (B) 1 µg/mL.
  • IHC - KHDC1 Antibody ASC11678
    Immunohistochemistry of KHDC1 in human liver tissue with KHDC1 antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q4VXA5
Other Accession NP_085045, 117956389
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 18 kDa

Observed: 26 kDa
Application Notes KHDC1 antibody can be used for detection of KHDC1 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 80759
Target/Specificity KHDC1; KHDC1 antibody is human, mouse and rat reactive. At least three isoforms of KHDC1 are known to exist; this antibody will only detect the longest isoform.
Reconstitution & Storage KHDC1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsKHDC1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KHDC1 (HGNC:21366)
Cellular Location Membrane; Multi-pass membrane protein
Citations (0)

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KHDC1 Antibody: KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins that are involved in various aspects of RNA metabolism, ranging from transcription to RNA splicing, transportation, translation, and stability (1). KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs (2,3). KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway and that the C-terminal putative trans-membrane motif (TMM) is critical for its activities (3,4).


Valverde R, Edwards L, and Regan L. Structure and function of KH domains. FEBS J. 2008; 275:2712–26.
Pierre A, Gautier M, Callebaut I, et al. Atypical structure and phylogenomic evolution of the new eutherian oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family. Genomics 2007; 90:583-94.

Cai C, Liu J, Wang C, et al. KHDC1A, a novel translational repressor, induces endoplasmic reticulum-dependent apoptosis. DNA Cell Biol. 2012; 31:1447-57.

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$ 335.00
Cat# ASC11678
Availability: 5-7days
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