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BTLA Antibody

  • WB - BTLA Antibody  ASC11697
    Western blot analysis of BTLA in Jurkat cell lysate at (A) 1 and (B) 2 µg/ml.
  • IHC - BTLA Antibody  ASC11697
    Immunohistochemistry of BTLA in human small intestine tissue with BTLA antibody at 2.5 µg/mL.
  • IF - BTLA Antibody  ASC11697
    Immunofluorescence of BTLA in human small intestine tissue with BTLA antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z6A9
Other Accession NP_861445, 145580621
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 32 kDa

Observed: 40kDa
Application Notes BTLA antibody can be used for detection of BTLA by Western blot at 1 - 2 µg/ml.
Additional Information
Gene ID 151888
Target/Specificity BTLA; BTLA antibody is human specific. At least two isoforms of BTLA are known to exist.
Reconstitution & Storage BTLA antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsBTLA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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The B- and T-lymphocyte attenuator (BTLA) protein is a member of the immunoglobulin superfamily containing a single immunoglobulin (Ig) domain (1). Like other coihibitory receptors such as CTLA-4 and PD-1, BTLA functions as a receptor that relays inhibitory signals to suppress the immune response, and can inhibit LPS-induced endotoxic shock by suppressing TLR4 signaling in innate immune cells (1,2). Polymorphisms in this gene have also been associated with an increased risk of rheumatoid arthritis (3).


Carreno BM and Collins M. BTLA: a new inhibitory receptor with a B7-like ligand. Trends Immunol. 2003; 24:524-7.
Kobayashi Y, Iwata A, Suzuki K, et al. B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells. Proc. Natl. Acad. Sci. USA 2013; 110:5121-6.
Lin SC, Kuo CC, and Chan CH. Association of a BTLA gene polymorphism with a risk of rheumatoid arthritis. J. Biomed. Sci. 2006; 13:853-60.

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$ 335.00
Cat# ASC11697
Availability: 5-7days
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