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TMIGD1 Antibody

  • WB - TMIGD1 Antibody ASC11739
    Western blot analysis of TMIGD1 in rat liver tissue lysate with TMIGD1 antibody at (A) 1 and (B) 2 µg/ml.
  • IHC - TMIGD1 Antibody ASC11739
    Immunohistochemistry of TMIGD1 in mouse liver tissue with TMIGD1 antibody at 5 µg/mL.
  • IF - TMIGD1 Antibody ASC11739
    Immunofluorescence of TMIGD1 in mouse liver tissue with TMIGD1 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6UXZ0
Other Accession NP_996663, 45592949
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 29 kDa

Observed: 24 kDa
Application Notes TMIGD1 antibody can be used for detection of TMIGD1 by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 388364
Target/Specificity TMIGD1; TMIGD1 antibody is human, mouse and rat reactive. At least two isoforms of TMIGD1 are known to exist; this antibody will detect both isoforms.
Reconstitution & Storage TMIGD1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsTMIGD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMIGD1 (HGNC:32431)
Function May control cell-cell adhesion, cell migration and proliferation, cell morphology, and protects renal epithelial cells from oxidative cell injury to promote cell survival.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cytoplasm
Research Areas
Citations (0)

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TMIGD1 (transmembrane and immunoglobulin domain containing 1) is a 262 amino acid single-pass membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains (1,2). It is a nonsecreted, glycosylated protein located in the cytoplasm and cell membrane (1). TMIGD1 might be a possible cell-differentiation marker in the intestine, whose expression is lost during cellular transformation and promote progression of tumorigenesis in the intestinal epithelium (2-4). TMIGD1 has also been postulated to play a role in cell adhesion (2).


Clark HF, Gurney AL, Abaya E, et al. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Res. 2003; 13:2265-70.
Fujimoto K, Beauchamp RD, Whitehead RH. Identification and isolation of candidate human colonic clonogenic cells based on cell surface integrin expression. Gastroenterology 2002; 123:1941–8.
Yan J, Jiang J, Lim CA, et al. Blimp-1 regulates cell growth through repression of p53 transcription. Proc. Natl. Acad. Sci. USA 2007; 104:1841-6.
Cattaneo E, Laczko E, Buffoli F, et al. Preinvasive colorectal lesion transcriptomes correlate with endoscopic morphology (polypoid vs. nonpolypoid). EMBO Mol Med. 2011; 3:334-47.

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$ 335.00
Cat# ASC11739
Availability: 5-7days
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