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MYH8 Antibody

  • WB - MYH8 Antibody ASC11887
    Western blot analysis of MYH8 in HeLa cell lysate with MYH8 antibody at (A) 0.5 and (B) 1 µg/ml.
  • IHC - MYH8 Antibody ASC11887
    Immunohistochemistry of MYH8 in mouse skeletal muscle tissue with MYH8 antibody at 5 µg/ml.
  • IF - MYH8 Antibody ASC11887
    Immunofluorescence of MYH8 in mouse skeletal muscle tissue with MYH8 antibody at 20 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13535
Other Accession NP_002463, 153945790
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 213 kDa

Observed: 220 kDa
Application Notes MYH8 antibody can be used for detection of MYH8 by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 4626
Target/Specificity MYH8; MYH8 antibody is human, mouse and rat reactive. MYH8 antibody is predicted to not cross-react with other members of the myosin heavy chain family.
Reconstitution & Storage MYH8 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsMYH8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYH8
Function Muscle contraction.
Cellular Location Cytoplasm, myofibril. Note=Thick filaments of the myofibrils
Citations (0)

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Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells (1). MYH8 (myosin, heavy chain 8, skeletal muscle, perinatal) is a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction (2,3). This gene is predominantly expressed in fetal skeletal muscle. MYH8 is regulated by phosphorylation via myosin light chain kinase (MLCK) and by intracellular Ca2+ concentrations (3). A mutation in this gene results in trismus-pseudocamptodactyly syndrome (4).


Yu H, Waddell JN, Kuang S, et al. Park7 expression influences myotube size and myosin expression in muscle. PLoS One 2014; 9:e92030.
Feghali R and Leinwand LA. Molecular genetic characterization of a developmentally regulated human perinatal myosin heavy chain. J. Cell Biol. 1989; 108:1791-7.
Jullian EH, Kelly AM, Pompidou AJ, et al. Characterization of a human perinatal myosin heavy-chain transcript. Eur. J. Biochem. 1995; 230:1001-6.
Minzer-Conzetti K, Wu E, Vargervik K, et al. Phenotypic variation in trismus-pseudocamptodactyly syndrome caused by a recurrent MYH8 mutation. Clin. Dysmorphol. 2008; 17:1-4.

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$ 335.00
Cat# ASC11887
Availability: 5-7days
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