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IKZF2 Antibody

  • WB - IKZF2 Antibody ASC11900
    Western blot analysis of IKZF2 in EL4 cell lysate with IKZF2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
  • IHC - IKZF2 Antibody ASC11900
    Immunohistochemistry of IKZF2 in human spleen tissue with IKZF2 antibody at 5 µg/mL.
  • IF - IKZF2 Antibody ASC11900
    Immunofluorescence of IKZF2 in human spleen tissue with IKZF2 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKS7
Other Accession NP_057344, 119220596
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 58 kDa

Observed: 60 kDa
Application Notes IKZF2 antibody can be used for detection of IKZF2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 22807
Target/Specificity IKZF2; IKZF2 antibody is human, mouse and rat reactive. At least two isoforms of IKZF2 are known to exist; this antibody will detect both isoforms. IKZF2 antibody is predicted to not cross-react with other IKZF proteins.
Reconstitution & Storage IKZF2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsIKZF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IKZF2
Synonyms HELIOS, ZNFN1A2
Function Associates with Ikaros at centromeric heterochromatin.
Cellular Location Nucleus.
Research Areas
Citations (0)

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The Ikaros family zinc finger 2 (IKZF2) is a member of the Ikaros family of zinc-finger proteins, a family of hematopoietic-specific transcription factors involved in the regulation of lymphocyte development (1,2). IKZF2 forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development (3). Its expression is a marker for T cell activation and proliferation (4).


Hahm K, Cobb BS, McCarty AS, et al. Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev. 1998; 12:782-96.
John LB and Ward AC. The Ikaros gene family: transcriptional regulators of hematopoiesis and immunity. Mol. Immunol. 2011; 48:1272-8.
Kelly CM, Ikeda T, Koipally J, et al. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr. Biol. 1998; 8:508-15.
Akimova T, Beier UH, Wang L, et al. Helios expression is a marker for T cell activation and proliferation. PLoS One 2011; 6:e24226.

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$ 335.00
Cat# ASC11900
Availability: 5-7days
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