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TENM1 Antibody

  • WB - TENM1 Antibody ASC11913
    Western blot analysis of TENM1 in human brain tissue lysate with TENM1 antibody at 1 µg/ml.
  • IHC - TENM1 Antibody ASC11913
    Immunohistochemistry of TENM1 in mouse brain tissue with TENM1 antibody at 5 µg/mL.
  • IF - TENM1 Antibody ASC11913
    Immunofluorescence of TENM1 in mouse brain tissue with TENM1 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKZ4
Other Accession NP_001156750, 253970444
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 301 kDa

Observed: 280 kDa
Application Notes TENM1 antibody can be used for detection of TENM1 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 10178
Target/Specificity TENM1; TENM1 antibody is human, mouse and rat reactive. TENM1 antibody is predicted to not cross-react with other members of the TENM family.
Reconstitution & Storage TENM1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsTENM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TENM1
Synonyms ODZ1, TNM1
Function Involved in neural development, regulating the establishment of proper connectivity within the nervous system. May function as a cellular signal transducer (By similarity).
Cellular Location Cell membrane; Single-pass membrane protein Teneurin C-terminal-associated peptide: Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with the dystroglycan complex at the cell membrane in hippocampal cells. Binds hippocampal cell membranes and is incorporated in the cytoplasm by endocytosis in a caveoli-dependent manner. Upon cell internalization is transported arround and in the nucleus (By similarity).
Tissue Location Expressed in fetal brain.
Research Areas
Citations (0)

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The teneurin transmembrane protein 1 (TENM1) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM1 is expressed primarily in the developing central nervous system and may be proteolytically cleaved with the intracellular domain translocating to the nucleus (3). TENM1 is a direct target of the homeobox transcription factor EMX2, a transcription factor thought to be important for area specification in the developing cortex (4).


Minet AD, Rubin BP, Tucker RP, et al. Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. J. Cell Sci. 1999; 112:2019-32.
Rubin BP, Tucker RP, Martin D, et al. Tenurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene Ten-m. Dev. Biol. 1999; 216:195-209.
Kenzelmann D, Chiquet-Ehrismann R, Leachman NT, et al. Teneurin-1 is expressed in interconnected regions of the developing brain and processed in vivo. BMC Dev. Biol. 2008; 8:30.
Beckmann J, Vitobello A, Ferralli J, et al. Human teneruin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter. BMC Dev. Biol. 2011; 11:35.

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$ 335.00
Cat# ASC11913
Availability: 5-7days
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