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GOLGIN97 Antibody

  • WB - GOLGIN97 Antibody ASC11937
    Western blot analysis of GOLGIN97 in human stomach tissue lysate with GOLGIN97 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking petpide.
  • IHC - GOLGIN97 Antibody ASC11937
    Immunohistochemistry of GOLGIN97 in rat stomach tissue with GOLGIN97 antibody at 5 µg/mL.
  • IF - GOLGIN97 Antibody ASC11937
    Immunofluorescence of GOLGIN97 in rat stomach tissue with GOLGIN97 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92805
Other Accession NP_002068, 4504063
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 84 kDa; Observed: 120 kDa
Application Notes GOLGIN97 antibody can be used for detection of GOLGIN97 by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 2800
Target/Specificity GOLGA1; GOLGIN97 antibody is human, mouse and rat reactive. At least two isoforms of GOLGIN97 are known to exist; this antibody will detect only the longer isoform. GOLGIN97 antibody is predicted to not cross-react with other GOLGIN family proteins.
Reconstitution & Storage GOLGIN97 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsGOLGIN97 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking.
Cellular Location Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9CW79}
Citations (0)

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GOLGIN97 was initially isolated as a Golgi complex autoantigen associated with Sjogren’s syndrome, a chronic autoimmune disease in which the body's white blood cells destroy the exocrine glands, specifically the salivary and lacrimal glands (1,2). GOLGIN97 plays a role as a tethering molecule in endosome to the trans-Golgi network (TGN) retrograde traffic (3). FIP1/RCP binding to GOLGIN97 is required for tethering and fusion of recycling endosome retrograde transport vesicles to the TGN (4).


Griffith KJ, Chan EK, Lung CC, et al. Molecular cloning of a novel 97-kd Golgi complex autoantigen associated with Sjogren’s syndrome. Arthritis Rheum. 1997; 40:1693-702.
Borchers AT, Naguwa SM, Keen CL, et al. Immunopathogenesis of Sjogren's syndrome. Clin. Rev. Allergy Immunol. 2003; 25:89-104.
Lu L, Tai G, and Hong W. Autoantigen Golgin-97, and effector of ARL1 GTPase, participates in traffic from the endosome to the trans-Golgi network. Mol. Biol. Cell 2004; 15:4426-43.
Jing J, Junutula JR, Wu C, et al. FIP1/RCP binding to Golgin-97 regulates retrograde transport from recycling endosomes to the trans-Golgi network. Mol. Biol. Cell 2010; 21:3041-53.

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$ 335.00
Cat# ASC11937
Availability: 5-7days
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