Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   Trophinin Antibody   

Trophinin Antibody

  • IHC - Trophinin Antibody ASC11944
    Immunohistochemistry of PD-L1 in human heart tissue with PD-L1 antibody at 2.5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q12816
Other Accession NP_001034794, 7216
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 78, 157 kDa

Observed: 94 kDa
Application Notes Trophinin antibody can be used for detection of Trophinin by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry at 10 μg/ml.
Additional Information
Gene ID 7216
Target/Specificity Trophinin antibody was raised against a 16 amino acid peptide near the amino terminus of human Trophinin.

The immunogen is located within amino acids 390 - 440 of Trophinin.
Reconstitution & Storage Trophinin antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsTrophinin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRO
Synonyms KIAA1114, MAGED3
Function Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion.
Tissue Location Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


Trophinin, also known as TRO or MAGED3, is an apical cell adhesion molecule that is implicated in the initial attachment during the process of embryo implantation and functions by mediating cell adhesion between trophoblastic and endometrial epithelial cells (1,2). Trophinin is a membrane protein expressed in chorionic villi trophoblasts and in maternal endometrial epithelial cells in an implantation-dependent manner and interacts with Bystin and Tastin, facilitating cell adhesion and embryo implantation (3,4). The induction of Trophinin expression may be a useful method for improving implantation rates and can be a potential diagnostic factor and biomarker for human cancer (4,5).


Fukuda MN, Sato T, Nakayama J, et al. Trophinin and tastin, a novel cell adhesion molecule complex with potential involvement in embryo implantation. Genes Dev. 1995; 9:1199-210.
Ma L, Yin M, Wu X, et al. Expression of trophinin and bystin identifies distinct cell types in the germinal zones of adult rat brain. Eur. J. Neurosci. 2006; 23:2265-76.
Tamura N, Sugihara K, Akama TO, et al. Trophinin-mediated cell adhesion induces apoptosis of human endometrial epithelial cells through PKC-d. Cell Cycle 2011; 10:135-43.
Chen KY, Lee YC, Lai JM, et al. Identification of trophinin as an enhancer for cell invasion and a prognostic factor for early stage lung cancer. Eur. J. Cancer. 2007; 43:782-90.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 335.00
Cat# ASC11944
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions