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SUSD3 Antibody

  • WB - SUSD3 Antibody ASC11969
    Western blot analysis of SUSD3 in HeLa cell lysate with SUSD3 antibody at 1 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96L08
Other Accession NP_659443, 21450717
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 16, 22, 23, 28 kDa

Observed: 23 kDa
Application Notes SUSD3 antibody can be used for the detection of SUSD3 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 203328
Target/Specificity SUSD3; SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.
Reconstitution & Storage SUSD3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsSUSD3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SUSD3
Function May play a role in breast tumorigenesis by promoting estrogen-dependent cell proliferation, cell-cell interactions and migration.
Cellular Location Cell membrane; Single-pass membrane protein. Note=Prominently localized to cell-cell borders.
Tissue Location Highly expressed in estrogen receptor-positive breast tumors.
Research Areas
Citations (0)

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Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).


Abba MC, Hu Y, Sun H, et al. Gene expression signature of estrogen receptor alpha status in breast cancer. BMC Genomics 2005; 6:37.
Parris TZ, Danielsson A, Nemes S, et al. Clinical implications of gene dosage and gene expression patterns in diploid breast cancer. Clin. Cancer Res. 2010; 16:3860-74.
Moy I, Todorovic V, Dubash AD, et al. Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells. Oncogene 2015; 34:323-33.

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$ 335.00
Cat# ASC11969
Availability: 5-7days
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