ADRM1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant ADRM1.
|Application ||WB, IF, IP, E|
|Calculated MW||42153 Da|
|Other Names||Proteasomal ubiquitin receptor ADRM1, 110 kDa cell membrane glycoprotein, Gp110, Adhesion-regulating molecule 1, ARM-1, Proteasome regulatory particle non-ATPase 13, hRpn13, Rpn13 homolog, ADRM1, GP110|
|Target/Specificity||ADRM1 (AAH17245.1, 18 a.a. ~ 407 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ADRM1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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The protein encoded by this gene is an integral plasma membrane protein which promotes cell adhesion. The encoded protein is thought to undergo O-linked glycosylation. Expression of this gene has been shown to be induced by gamma interferon in some cancer cells. Two transcript variants encoding the same protein have been found for this gene.
1.Phospho-?GNp63 ? /Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells.Huang Y, Ratovitski EA.Aging (Albany NY). 2010 Dec;2(12):959-68.2.Phosphorylated TP63 Induces Transcription of RPN13, Leading to NOS2 Protein Degradation.Huang Y, Ratovitski EA.J Biol Chem. 2010 Dec 31;285(53):41422-31. Epub 2010 Oct 19.3.Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content.Pece S, Tosoni D, Confalonieri S, Mazzarol G, Vecchi M, Ronzoni S, Bernard L, Viale G, Pelicci PG, Di Fiore PP.Cell. 2010 Jan 8;140(1):62-73.
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