CAMK4 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant CAMK4.
|Application ||WB, IHC, IF|
|Calculated MW||51926 Da|
|Other Names||Calcium/calmodulin-dependent protein kinase type IV, CaMK IV, CaM kinase-GR, CAMK4, CAMK, CAMK-GR, CAMKIV|
|Target/Specificity||CAMK4 (AAH25687.1, 1 a.a. ~ 473 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||CAMK4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
1.Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade: a potential mechanism of inflammatory pain.Nakanishi M, Hata K, Nagayama T, Sakurai T, Nishisho T, Wakabayashi H, Hiraga T, Ebisu S, Yoneda T.Mol Biol Cell. 2010 Aug 1;21(15):2568-77. Epub 2010 Jun 9.
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