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CLCN2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant CLCN2.

  • WB - CLCN2 Antibody (monoclonal) (M01) AT1550a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (64.24 KDa) .
  • WB - CLCN2 Antibody (monoclonal) (M01) AT1550a
    CLCN2 monoclonal antibody (M01), clone 3E1 Western Blot analysis of CLCN2 expression in Hela S3 NE ( (Cat # AT1550a )
  • WB - CLCN2 Antibody (monoclonal) (M01) AT1550a
    Western Blot analysis of CLCN2 expression in transfected 293T cell line by CLCN2 monoclonal antibody (M01), clone 3E1.

    Lane 1: CLCN2 transfected lysate(96.8 KDa).
    Lane 2: Non-transfected lysate.
  • WB - CLCN2 Antibody (monoclonal) (M01) AT1550a
    Western blot analysis of CLCN2 over-expressed 293 cell line, cotransfected with CLCN2 Validated Chimera RNAi ( (Cat # AT1550a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51788
Other Accession BC021578
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 30
Calculated MW 98535 Da
Additional Information
Gene ID 1181
Other Names Chloride channel protein 2, ClC-2, CLCN2
Target/Specificity CLCN2 (AAH21578.1, 38 a.a. ~ 387 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCLCN2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations ( 0 )


The transmembrane protein encoded by this gene is a voltage-gated chloride channel that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.


Analysis of CLCN2 as candidate gene for megalencephalic leukoencephalopathy with subcortical cysts. Scheper GC, et al. Genet Test Mol Biomarkers, 2010 Apr. PMID 20187760. Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval. Cornejo I, et al. J Cell Physiol, 2009 Dec. PMID 19711355. CLCN2 variants in idiopathic generalized epilepsy. Kleefuss-Lie A, et al. Nat Genet, 2009 Sep. PMID 19710712. Isolation and characterization of a high affinity peptide inhibitor of ClC-2 chloride channels. Thompson CH, et al. J Biol Chem, 2009 Sep 18. PMID 19574231. PIKfyve-dependent regulation of the Cl- channel ClC-2. Klaus F, et al. Biochem Biophys Res Commun, 2009 Apr 10. PMID 19232516.

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$ 350.00
Cat# AT1550a
Availability: 7-10 days
Bulk Size
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