EIF2AK2 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant EIF2AK2.
|Application ||WB, IHC, IF, E|
|Calculated MW||62094 Da|
|Other Names||Interferon-induced, double-stranded RNA-activated protein kinase, Eukaryotic translation initiation factor 2-alpha kinase 2, eIF-2A protein kinase 2, Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase RNA-activated, PKR, Protein kinase R, Tyrosine-protein kinase EIF2AK2, p68 kinase, EIF2AK2, PKR, PRKR|
|Target/Specificity||EIF2AK2 (NP_002750, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||EIF2AK2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1.PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis.Cheng X, Bennett RL, Liu X, Byrne M, Stratford May WBlood Cancer J. 2013 Sep 6;3:e144. doi: 10.1038/bcj.2013.42.2.PKR regulates proliferation, differentiation and survival of murine hematopoietic stem/progenitor cells.Liu X, Bennett RL, Cheng X, Byrne M, Reinhard MK, May WS JrBlood. 2013 Feb 14.3.Increased Expression of the dsRNA-Activated Protein Kinase PKR in Breast Cancer Promotes Sensitivity to Doxorubicin.Bennett RL, Carruthers AL, Hui T, Kerney KR, Liu X, May WS Jr.PLoS One. 2012;7(9):e46040. doi: 10.1371/journal.pone.0046040. Epub 2012 Sep 24.
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