FZD3 Antibody (monoclonal) (M09)
Mouse monoclonal antibody raised against a partial recombinant FZD3.
|Application ||WB, IF, E|
|Calculated MW||76263 Da|
|Other Names||Frizzled-3, Fz-3, hFz3, FZD3|
|Target/Specificity||FZD3 (NP_059108, 55 a.a. ~ 157 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||FZD3 Antibody (monoclonal) (M09) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development.
Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression. Inkster B, et al. Neuroimage, 2010 Nov 15. PMID 20219685.Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer. Kawano Y, et al. Br J Cancer, 2009 Apr 7. PMID 19277043.Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence. Greg?rio SP, et al. Psychiatry Res, 2009 Jan 30. PMID 19054571.Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells. Wang HX, et al. Mol Hum Reprod, 2009 Jan. PMID 19038973.The Frizzled 3 gene is associated with methamphetamine psychosis in the Japanese population. Kishimoto M, et al. Behav Brain Funct, 2008 Aug 15. PMID 18702828.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.