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FZR1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a full-length recombinant FZR1.

  • WB - FZR1 Antibody (monoclonal) (M02) AT2132a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (80.08 KDa) .
  • WB - FZR1 Antibody (monoclonal) (M02) AT2132a
    FZR1 monoclonal antibody (M02), clone 4C4. Western Blot analysis of FZR1 expression in Hela S3 NE.
  • IHC - FZR1 Antibody (monoclonal) (M02) AT2132a
    Immunoperoxidase of monoclonal antibody to FZR1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
  • E - FZR1 Antibody (monoclonal) (M02) AT2132a
    Detection limit for recombinant GST tagged FZR1 is 1 ng/ml as a capture antibody.
  •  - FZR1 Antibody (monoclonal) (M02) AT2132a
    Proximity Ligation Analysis of protein-protein interactions between CCNB1 and FZR1. HeLa cells were stained with anti-CCNB1 rabbit purified polyclonal 1:1200 and anti-FZR1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UM11
Other Accession BC013413
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4C4
Calculated MW 55179 Da
Additional Information
Gene ID 51343
Other Names Fizzy-related protein homolog, Fzr, CDC20-like protein 1, Cdh1/Hct1 homolog, hCDH1, FZR1, CDH1, FYR, FZR, KIAA1242
Target/Specificity FZR1 (AAH13413.1, 1 a.a. ~ 493 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsFZR1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation. Naoe H, et al. Mol Cell Biol, 2010 Aug. PMID 20530197.Centrosome-related genes, genetic variation, and risk of breast cancer. Olson JE, et al. Breast Cancer Res Treat, 2010 May 28. PMID 20508983.Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis. Sigl R, et al. J Cell Sci, 2009 Nov 15. PMID 19861496.The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Bassermann F, et al. Cell, 2008 Jul 25. PMID 18662541.Dissection of the APCCdh1-Skp2 cascade in breast cancer. Fujita T, et al. Clin Cancer Res, 2008 Apr 1. PMID 18381934.

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$ 350.00
Cat# AT2132a
Availability: 7-10 days
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