GSTP1 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant GSTP1.
|Application ||WB, IF, IP|
|Calculated MW||23356 Da|
|Other Names||Glutathione S-transferase P, GST class-pi, GSTP1-1, GSTP1, FAEES3, GST3|
|Target/Specificity||GSTP1 (AAH10915, 1 a.a. ~ 210 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||GSTP1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
1.Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization.Kan CY, Wen VW, Pasquier E, Jankowski K, Chang M, Richards LA, Kavallaris M, Mackenzie KL.Oncogene. 2012 Feb 6. doi: 10.1038/onc.2011.645. [Epub ahead of print]
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