HELZ Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant HELZ.
|Application ||WB, IHC, IF, E|
|Calculated MW||218970 Da|
|Other Names||Probable helicase with zinc finger domain, 364-, Down-regulated in human cancers protein, HELZ, DRHC, KIAA0054|
|Target/Specificity||HELZ (NP_055692, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||HELZ Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 [PubMed 10471385]).
1.The Putative RNA Helicase HELZ Promotes Cell Proliferation, Translation Initiation and Ribosomal Protein S6 Phosphorylation.Hasgall PA, Hoogewijs D, Faza MB, Panse VG, Wenger RH, Camenisch G.PLoS One. 2011;6(7):e22107. Epub 2011 Jul 13.
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