NDRG1 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a full length recombinant NDRG1.
|Application ||WB, IHC, IF, E|
|Calculated MW||42835 Da|
|Other Names||Protein NDRG1, Differentiation-related gene 1 protein, DRG-1, N-myc downstream-regulated gene 1 protein, Nickel-specific induction protein Cap43, Reducing agents and tunicamycin-responsive protein, RTP, Rit42, NDRG1, CAP43, DRG1, RTP|
|Target/Specificity||NDRG1 (AAH03175, 1 a.a. ~ 394 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||NDRG1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified.
1.A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1).Jiang K, Shen Z, Ye Y, Yang X, Wang S.Scand J Gastroenterol. 2010 Apr 14. [Epub ahead of print]2.Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry.Leth-Larsen R, Lund R, Hansen HV, Laenkholm AV, Tarin D, Jensen ON, Ditzel HJ.Mol Cell Proteomics. 2009 Jun;8(6):1436-49. Epub 2009 Mar 24.
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