NDRG4 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a full length recombinant NDRG4.
|Application ||WB, IHC, E|
|Calculated MW||38459 Da|
|Other Names||Protein NDRG4, Brain development-related molecule 1, N-myc downstream-regulated gene 4 protein, Vascular smooth muscle cell-associated protein 8, SMAP-8, NDRG4, BDM1, KIAA1180|
|Target/Specificity||NDRG4 (AAH11795.1, 1 a.a. ~ 339 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||NDRG4 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
1.NDRG4 is Downregulated in Glioblastoma and Inhibits Cell Proliferation.Ding W, Zhang J, Yoon JG, Shi D, Foltz G, Lin B.OMICS. 2012 May;16(5):263-7. Epub 2012 Apr 10.2.N-Myc Downstream-Regulated Gene 4 (NDRG4): A Candidate Tumor Suppressor Gene and Potential Biomarker for Colorectal Cancer.Melotte V, Lentjes MH, van den Bosch SM, Hellebrekers DM, de Hoon JP, Wouters KA, Daenen KL, Partouns-Hendriks IE, Stessels F, Louwagie J, Smits KM, Weijenberg MP, Sanduleanu S, Khalid-de Bakker CA, Oort FA, Meijer GA, Jonkers DM, Herman JG, de Bruine AP,J Natl Cancer Inst. 2009 Jul 1;101(13):916-27. Epub 2009 Jun 17.3.Identification and action of N-myc downstream regulated gene 4 A2 in rat pancreas.Wang JF, Hill DJ.J Endocrinol. 2009 Apr;201(1):15-25. Epub 2009 Feb 4.
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