RFP2 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant RFP2.
|Other Names||Potassium channel regulatory protein, Potassium channel regulator, Protein CLLD4, KCNRG, CLLD4|
|Target/Specificity||RFP2 (NP_005789, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||RFP2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This gene is located on chromosome 13 within the minimal deletion region for B-cell chronic lymphocytic leukemia. Multiple alternatively spliced transcript variants have been found for this gene.
Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD. Lerner M, et al. Mol Biol Cell, 2007 May. PMID 17314412.Human RFP2 gene promoter: unique structure and unusual strength. Skoblov M, et al. Biochem Biophys Res Commun, 2006 Apr 14. PMID 16499869.The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse. Corcoran MM, et al. Genes Chromosomes Cancer, 2004 Aug. PMID 15188451.
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