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SAV1 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant SAV1.

  • WB - SAV1 Antibody (monoclonal) (M02) AT3774a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.98 KDa) .
  • WB - SAV1 Antibody (monoclonal) (M02) AT3774a
    SAV1 monoclonal antibody (M02), clone 3B2. Western Blot analysis of SAV1 expression in HepG2 ( (Cat # AT3774a )
  • WB - SAV1 Antibody (monoclonal) (M02) AT3774a
    SAV1 monoclonal antibody (M02), clone 3B2 Western Blot analysis of SAV1 expression in Hela S3 NE ( (Cat # AT3774a )
  • IF - SAV1 Antibody (monoclonal) (M02) AT3774a
    Immunofluorescence of monoclonal antibody to SAV1 on HeLa cell. [antibody concentration 60 ug/ml]
  • IP - SAV1 Antibody (monoclonal) (M02) AT3774a
    Immunoprecipitation of SAV1 transfected lysate using anti-SAV1 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SAV1 MaxPab rabbit polyclonal antibody.
  • E - SAV1 Antibody (monoclonal) (M02) AT3774a
    Detection limit for recombinant GST tagged SAV1 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H4B6
Other Accession NM_021818
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 3B2
Calculated MW 44634 Da
Additional Information
Gene ID 60485
Other Names Protein salvador homolog 1, 45 kDa WW domain protein, hWW45, SAV1, WW45
Target/Specificity SAV1 (NP_068590, 300 a.a. ~ 383 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSAV1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously expressed in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.


1.Hippo signaling mediates proliferation, invasiveness and metastatic potential of clear cell renal cell carcinoma.Schutte U, Bisht S, Heukamp LC, Kebschull M, Florin A, Haarmann J, Hoffmann P, Bendas G, Buettner R, Brossart P, Feldmann G.Translational Oncology Volume 7, Issue 2, April 2014, Pages 309–3212.Screening of binding proteins that interact with human Salvador 1 in a human fetal liver cDNA library by the yeast two-hybrid system.Li X, Luo X, Li Z, Wang G, Xiao H, Tao D, Gong J, Hu J.Mol Biol Rep. 2012 May 9.3.Mammalian Ste20-Like Kinase and SAV1 Promote 3T3-L1 Adipocyte Differentiation by Activation of PPAR?^.Park BH, Kim DS, Won GW, Jeon HJ, Oh BC, Lee Y, Kim EG, Lee YH.PLoS One. 2012;7(1):e30983. Epub 2012 Jan 26.4.LATS2 Is a Tumor Suppressor Gene of Malignant Mesothelioma.Murakami H, Mizuno T, Taniguchi T, Fujii M, Ishiguro F, Fukui T, Akatsuka S, Horio Y, Hida T, Kondo Y, Toyokuni S, Osada H, Sekido Y.Cancer Res. 2011 Feb 1;71(3):873-83. Epub 2011 Jan 18.5.Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction.Mardin BR, Lange C, Baxter JE, Hardy T, Scholz SR, Fry AM, Schiebel E.Nat Cell Biol. 2010 Dec;12(12):1166-76. Epub 2010 Nov 14.

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$ 350.00
Cat# AT3774a
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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