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SGCB Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant SGCB.

  • WB - SGCB Antibody (monoclonal) (M02) AT3853a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - SGCB Antibody (monoclonal) (M02) AT3853a
    SGCB monoclonal antibody (M02), clone 1C10 Western Blot analysis of SGCB expression in MCF-7 ( (Cat # AT3853a )
  • IHC - SGCB Antibody (monoclonal) (M02) AT3853a
    Immunoperoxidase of monoclonal antibody to SGCB on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml]
  • IF - SGCB Antibody (monoclonal) (M02) AT3853a
    Immunofluorescence of monoclonal antibody to SGCB on MCF-7 cell . [antibody concentration 10 ug/ml]
  • E - SGCB Antibody (monoclonal) (M02) AT3853a
    Detection limit for recombinant GST tagged SGCB is 0.1 ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16585
Other Accession NM_000232
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 1C10
Calculated MW 34777 Da
Additional Information
Gene ID 6443
Other Names Beta-sarcoglycan, Beta-SG, 43 kDa dystrophin-associated glycoprotein, 43DAG, A3b, SGCB
Target/Specificity SGCB (NP_000223, 87 a.a. ~ 196 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSGCB Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.


Sarcoglycanopathies: can muscle immunoanalysis predict the genotype? Klinge L, et al. Neuromuscul Disord, 2008 Dec. PMID 18996010.Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation. Sharma P, et al. Am J Physiol Lung Cell Mol Physiol, 2008 Jan. PMID 17993586.The beta-delta-core of sarcoglycan is essential for deposition at the plasma membrane. Draviam RA, et al. Muscle Nerve, 2006 Dec. PMID 17036316.Muscle protein analysis in the detection of heterozygotes for recessive limb girdle muscular dystrophy type 2B and 2E. Fanin M, et al. Neuromuscul Disord, 2006 Nov. PMID 16934466.Homozygous microdeletion of chromosome 4q11-q12 causes severe limb-girdle muscular dystrophy type 2E with joint hyperlaxity and contractures. Kaindl AM, et al. Hum Mutat, 2005 Sep. PMID 16088906.

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$ 350.00
Cat# AT3853a
Availability: 7-10 days
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