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SNX1 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant SNX1.

  • WB - SNX1 Antibody (monoclonal) (M01) AT3984a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
  • WB - SNX1 Antibody (monoclonal) (M01) AT3984a
    SNX1 monoclonal antibody (M01), clone 6H1 Western Blot analysis of SNX1 expression in HeLa ( (Cat # AT3984a )
  • WB - SNX1 Antibody (monoclonal) (M01) AT3984a
    Western Blot analysis of SNX1 expression in transfected 293T cell line by SNX1 monoclonal antibody (M01), clone 6H1.

    Lane 1: SNX1 transfected lysate(59.1 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - SNX1 Antibody (monoclonal) (M01) AT3984a
    Immunoperoxidase of monoclonal antibody to SNX1 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]
  • E - SNX1 Antibody (monoclonal) (M01) AT3984a
    Detection limit for recombinant GST tagged SNX1 is approximately 0.03ng/ml as a capture antibody.
  • WB - SNX1 Antibody (monoclonal) (M01) AT3984a
    Western blot analysis of SNX1 over-expressed 293 cell line, cotransfected with SNX1 Validated Chimera RNAi ( (Cat # AT3984a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13596
Other Accession NM_003099
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 6H1
Calculated MW 59070 Da
Additional Information
Gene ID 6642
Other Names Sorting nexin-1, SNX1
Target/Specificity SNX1 (NP_003090, 166 a.a. ~ 275 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsSNX1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.


Regulation of P2Y1 receptor traffic by sorting Nexin 1 is retromer independent. Nisar S, et al. Traffic, 2010 Apr. PMID 20070609.SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors. Mari M, et al. Traffic, 2008 Mar. PMID 18088323.EGF induces macropinocytosis and SNX1-modulated recycling of E-cadherin. Bryant DM, et al. J Cell Sci, 2007 May 15. PMID 17502486.Sorting nexin 1 down-regulation promotes colon tumorigenesis. Nguyen LN, et al. Clin Cancer Res, 2006 Dec 1. PMID 17145813.Interchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptors. Rojas R, et al. Mol Cell Biol, 2007 Feb. PMID 17101778.

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$ 350.00
Cat# AT3984a
Availability: 7-10 days
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