SOX9 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant SOX9.
|Application ||WB, IHC, IF, IP|
|Calculated MW||56137 Da|
|Other Names||Transcription factor SOX-9, SOX9|
|Target/Specificity||SOX9 (NP_000337, 400 a.a. ~ 509 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||SOX9 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
1.Expression of cancer stem cell markers is more frequent in anaplastic thyroid carcinoma compared to papillary thyroid carcinoma and is related to adverse clinical outcome.Yun JY, Kim YA, Choe JY, Min H, Lee KS, Jung Y, Oh S, Kim JEJ Clin Pathol. 2013 Aug 28. doi: 10.1136/jclinpath-2013-201711.2.Supra- and infratentorial pediatric ependymomas differ significantly in NeuN, p75 and GFAP expression.Hagel C, Treszl A, Fehlert J, Harder J, von Haxthausen F, Kern M, von Bueren AO, Kordes UJ Neurooncol. 2013 Apr;112(2):191-7. doi: 10.1007/s11060-013-1062-1. Epub 2013 Jan 31.3.A Molecular Profile of Focal Segmental Glomerulosclerosis from Formalin-Fixed, Paraffin-Embedded Tissue.Hodgin JB, Borczuk AC, Nasr SH, Markowitz GS, Nair V, Martini S, Eichinger F, Vining C, Berthier CC, Kretzler M, D'Agati VD.Am J Pathol. 2010 Oct;177(4):1674-86. Epub 2010 Sep 16.
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