ACTA1/α-actin Antibody (C-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
|Application ||WB, IHC-P, IF, FC, E|
|Other Accession||P68136, P68135, P68137, P68134, P68139, P68138, P04751, P68035, P68033, P68032, P68034, Q3ZC07, P62738, P62740, P62737, P62736, P08023, P62739, P04752, P10995, NP_001091.1|
|Predicted||Xenopus, Bovine, Chicken, Mouse, Rabbit, Rat, Pig|
|Calculated MW||H=42;M=42;Rat=42 KDa|
|Antigen Region||346-375 aa|
|Other Names||ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-actin-1|
|Target/Specificity||This ACTA1/Alpha-actin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the C-terminal region of human ACTA1/Alpha-actin.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACTA1/α-actin Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.|
|Cellular Location||Cytoplasm, cytoskeleton.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Kim, E.Y., et al. Am. J. Physiol. Renal Physiol. 299 (3), F594-F604 (2010) :
Haigh, S.E., et al. Neuromuscul. Disord. 20(6):363-374(2010)
Yu, G., et al. J Clin Neurosci 17(6):766-769(2010)
Yu, C.H., et al. PLoS ONE 5 (7), E11878 (2010) :
Licastro, F., et al. Curr. Pharm. Des. 16(7):783-788(2010)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.