Purified Rabbit Polyclonal Antibody (Pab)
|Application ||WB, IHC-P, FC, E|
|Calculated MW||H=12 KDa|
|Other Names||C-C motif chemokine 15, Chemokine CC-2, HCC-2, Leukotactin-1, LKN-1, MIP-1 delta, Macrophage inflammatory protein 5, MIP-5, Mrp-2b, NCC-3, Small-inducible cytokine A15, CCL15(22-92), CCL15(25-92), CCL15(29-92), CCL15, MIP5, NCC3, SCYA15|
|Target/Specificity||This CCL15 antibody is generated from a rabbit immunized with a recombinant protein.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCL15 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MIP5, NCC3, SCYA15|
|Function||Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.|
|Tissue Location||Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients|
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Provided below are standard protocols that you may find useful for product applications.
Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
Youn B.-S.,et al.J. Immunol. 159:5201-5205(1997).
Wang W.,et al.J. Clin. Immunol. 18:214-222(1998).
Pardigol A.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:6308-6313(1998).
Nomiyama H.,et al.J. Interferon Cytokine Res. 19:227-234(1999).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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