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BSCL2 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96G97
Other Accession NP_001116427.1, NP_001124174.1, NP_116056.3
Clone Names 80722027
Peptide ID 80722027
Additional Information
Gene ID 26580
Other Names Seipin, Bernardinelli-Seip congenital lipodystrophy type 2 protein, BSCL2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name BSCL2
Function Is a regulator of lipid catabolism essential for adipocyte differentiation. May also be involved in the central regulation of energy homeostasis (By similarity). Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Expressed in motor neurons in the spinal cord and cortical neurons in the frontal lobe (at protein level) Highly expressed in brain, testis and adipose tissue
Research Areas
Citations (0)

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This gene encodes protein seipin, which is located in theendoplasmic reticulum and may be important for lipid dropletmorphology. Mutations in this gene have been associated withcongenital generalized lipodystrophy type 2 or Berardinelli-Seipsyndrome, a rare autosomal recessive disease characterized by anear absence of adipose tissue and severe insulin resistance.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.


Rakocevic-Stojanovic, V., et al. J. Neurol. Sci. 296 (1-2), 107-109 (2010) :Luigetti, M., et al. Muscle Nerve 42(3):448-451(2010)Nishiyama, A., et al. Pediatr Int 51(6):775-779(2009)Wu, Y.R., et al. J. Neurol. Neurosurg. Psychiatr. 80(10):1180-1181(2009)Chen, W., et al. Endocrinology 150(10):4552-4561(2009)

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$ 99.00
Cat# BP10112a
Availability: In Stock
Bulk Size
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