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FPRL1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P25090
Other Accession NP_001005738.1, NP_001453.1
Clone Names 90625034
Peptide ID 90625034
Additional Information
Gene ID 2358
Other Names N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, HM63, Lipoxin A4 receptor, LXA4 receptor, RFP, FPR2, FPRH1, FPRL1, LXA4R
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FPR2
Synonyms FPRH1, FPRL1, LXA4R
Function Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors (PubMed:1374236). Binding of FMLP to the receptor causes activation of neutrophils (PubMed:1374236). This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (PubMed:1374236). The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4) (PubMed:9547339). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Note=Associates with Amyloid-beta protein 42, product of APP, at the cell surface and the complex is then rapidly internalized.
Tissue Location Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis
Research Areas
Citations (0)

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Yang, E.M., et al. Ann. Allergy Asthma Immunol. 105(1):96-97(2010)Kretschmer, D., et al. Cell Host Microbe 7(6):463-473(2010)Lee, H.Y., et al. Exp. Mol. Med. 42(4):302-309(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Kim, S.D., et al. J. Immunol. 183(9):5511-5517(2009)

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$ 99.00
Cat# BP10206c
Availability: In Stock
Bulk Size
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