|Other Names||Breast cancer metastasis-suppressor 1-like protein, BRMS1-homolog protein p40, BRMS1-like protein p40, BRMS1L|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene shows sequence similarityto the human breast carcinoma metastasis suppressor (BRMS1) proteinand the mammalian Sds3 (suppressor of defective silencing 3)proteins. This protein is a component of the mSin3a family ofhistone deacetylase complexes (HDAC).
Lamesch, P., et al. Genomics 89(3):307-315(2007)Nikolaev, A.Y., et al. Biochem. Biophys. Res. Commun. 323(4):1216-1222(2004)
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