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ALX4 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9H161
Other Accession NP_068745.2
Clone Names 90723012
Peptide ID 90723012
Additional Information
Gene ID 60529
Other Names Homeobox protein aristaless-like 4, ALX4, KIAA1788
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALX4
Synonyms KIAA1788
Function Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138, ECO:0000269|PubMed:19692347}
Tissue Location Expression is likely to be restricted to bone. Found in parietal bone
Research Areas
Citations (0)

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This gene encodes a paired-like homeodomain transcriptionfactor expressed in the mesenchyme of developing bones, limbs,hair, teeth, and mammary tissue. Mutations in this gene causeparietal foramina 2 (PFM2); an autosomal dominant diseasecharacterized by deficient ossification of the parietal bones.Mutations in this gene also cause a form of frontonasal dysplasiawith alopecia and hypogonadism; suggesting a role for this gene incraniofacial development, mesenchymal-epithelial communication, andhair follicle development. Deletion of a segment of chromosome 11containing this gene, del(11)(p11p12), causes Potocki-Shaffersyndrome (PSS); a syndrome characterized by craniofacial anomalies,mental retardation, multiple exostoses, and genital abnormalitiesin males. In mouse, this gene has been shown to use dualtranslation initiation sites located 16 codons apart. [provided byRefSeq].


Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Tanzer, M., et al. PLoS ONE 5 (2), E9061 (2010) :Kayserili, H., et al. Hum. Mol. Genet. 18(22):4357-4366(2009)Chang, H., et al. J. Clin. Pathol. 62(10):908-914(2009)Drenos, F., et al. Hum. Mol. Genet. 18(12):2305-2316(2009)

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$ 99.00
Cat# BP10386c
Availability: In Stock
Bulk Size
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