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CLYBL Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8N0X4
Other Accession NP_996531.1
Clone Names 90904106
Peptide ID 90904106
Additional Information
Gene ID 171425
Other Names Citrate lyase subunit beta-like protein, mitochondrial, Citrate lyase beta-like, 41--, CLYBL, CLB
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLYBL (HGNC:18355)
Synonyms CLB
Function Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism (PubMed:29056341). Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5- dicarboxylate catabolism pathway (PubMed:29056341). The C5- dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite (PubMed:29056341). Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate (PubMed:24334609, PubMed:29056341). Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate (PubMed:24334609, PubMed:29056341). Also has very weak citramalate synthase activity in vitro (PubMed:24334609, PubMed:29056341).
Cellular Location Mitochondrion {ECO:0000250|UniProtKB:Q8R4N0}
Research Areas
Citations (0)

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Lasky-Su, J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1345-1354 (2008) :Morikawa, J., et al. Biochem. Biophys. Res. Commun. 289(5):1282-1286(2001)

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$ 80.00
Cat# BP10440a
Availability: In Stock
Bulk Size
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