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FNIP2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9P278
Other Accession NP_065891.1
Clone Names 91218156
Peptide ID 91218156
Additional Information
Gene ID 57600
Other Names Folliculin-interacting protein 2, FNIP1-like protein, O6-methylguanine-induced apoptosis 1 protein, FNIP2, FNIPL, KIAA1450, MAPO1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FNIP2
Synonyms FNIPL, KIAA1450, MAPO1
Function Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1 (PubMed:27353360). May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine- mispaired lesions (By similarity). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways (PubMed:18403135). May regulate phosphorylation of RPS6KB1 (PubMed:18663353).
Cellular Location Cytoplasm Note=Colocalizes with FLCN in the cytoplasm
Tissue Location Widely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenta and pancreas. Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue (PubMed:18403135). Higher levels detected in oncocytoma tumors than in normal kidney. Higher levels detected in renal cell carcinoma tumors than in normal kidney tissue (PubMed:27353360).
Research Areas
Citations (0)

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Rose, J. Phd, et al. Mol. Med. (2010) In press :Hasumi, H., et al. Gene 415 (1-2), 60-67 (2008) :

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$ 80.00
Cat# BP10654b
Availability: In Stock
Bulk Size
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