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MPP1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q00013
Clone Names 90904151
Peptide ID 90904151
Additional Information
Gene ID 4354
Other Names 55 kDa erythrocyte membrane protein, p55, Membrane protein, palmitoylated 1, MPP1, DXS552E, EMP55
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPP1
Synonyms DXS552E, EMP55
Function Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
Cellular Location Membrane; Lipid-anchor. Cell projection, stereocilium. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity) Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non- myelin-forming Schwann cells.
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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This gene encodes the prototype of the membrane-associatedguanylate kinase (MAGUK) family proteins. MAGUKs interact with thecytoskeleton and regulate cell proliferation, signaling pathways,and intercellular junctions. The encoded protein is an extensivelypalmitoylated membrane phosphoprotein containing a PDZ domain, aSrc homology 3 (SH3) motif, and a guanylate kinase domain. Thisgene product interacts with various cytoskeletal proteins and celljunctional proteins in different tissue and cell types, and may beinvolved in the regulation of cell shape, hair cell development,neural patterning of the retina, and apico-basal polarity and tumorsuppression pathways in non-erythroid cells. Multiple transcriptvariants encoding different isoforms have been found for this gene.


Seo, P.S., et al. Exp. Biol. Med. (Maywood) 234(3):255-262(2009)Seo, P.S., et al. Biochim. Biophys. Acta 1793(2):281-289(2009)Gosens, I., et al. Hum. Mol. Genet. 16(16):1993-2003(2007)Kusunoki, H., et al. Proteins 64(3):804-807(2006)Funke, L., et al. Annu. Rev. Biochem. 74, 219-245 (2005) :

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$ 80.00
Cat# BP10708c
Availability: In Stock
Bulk Size
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