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GPAA1 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O43292
Clone Names 91013043
Peptide ID 91013043
Additional Information
Gene ID 8733
Other Names Glycosylphosphatidylinositol anchor attachment 1 protein, GPI anchor attachment protein 1, GAA1 protein homolog, hGAA1, GPAA1, GAA1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPAA1
Synonyms GAA1
Function Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Ubiquitously expressed in fetal and adult tissues. Expressed at higher levels in fetal tissues than adult tissues.
Research Areas
Citations (0)

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Posttranslational glycosylphosphatidylinositol (GPI)anchor attachment serves as a general mechanism for linkingproteins to the cell surface membrane. The protein encoded by thisgene presumably functions in GPI anchoring at the GPI transferstep. The mRNA transcript is ubiquitously expressed in both fetaland adult tissues. The anchor attachment protein 1 contains anN-terminal signal sequence, 1 cAMP- and cGMP-dependent proteinkinase phosphorylation site, 1 leucine zipper pattern, 2 potentialN-glycosylation sites, and 8 putative transmembrane domains.


Jiang, W.W., et al. Mol. Cancer 6, 74 (2007) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Ho, J.C., et al. Int. J. Cancer 119(6):1330-1337(2006)Vainauskas, S., et al. J. Biol. Chem. 280(16):16402-16409(2005)Vainauskas, S., et al. J. Biol. Chem. 279(8):6540-6545(2004)

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$ 80.00
Cat# BP10722a
Availability: In Stock
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