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GPD1L Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8N335
Clone Names 91013045
Peptide ID 91013045
Additional Information
Gene ID 23171
Other Names Glycerol-3-phosphate dehydrogenase 1-like protein, GPD1-L, GPD1L, KIAA0089
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPD1L
Synonyms KIAA0089
Function Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
Cellular Location Cytoplasm. Note=Localized to the region of the plasma membrane
Tissue Location Most highly expressed in heart tissue, with lower levels in the skeletal muscle, kidney, lung and other organs.
Research Areas
Citations (0)

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The protein encoded by this gene catalyzes the conversionof sn-glycerol 3-phosphate to glycerone phosphate. The encodedprotein is found in the cytoplasm, associated with the plasmamembrane, where it binds the sodium channel, voltage-gated, type V,alpha subunit (SCN5A). Defects in this gene are a cause of Brugadasyndrome type 2 (BRS2) as well as sudden infant death syndrome(SIDS).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Liu, M., et al. Circ. Res. 105(8):737-745(2009)Valdivia, C.R., et al. Am. J. Physiol. Heart Circ. Physiol. 297 (4), H1446-H1452 (2009) :Makiyama, T., et al. Circ. J. 72(10):1705-1706(2008)London, B., et al. Circulation 116(20):2260-2268(2007)

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$ 80.00
Cat# BP10723a
Availability: In Stock
Bulk Size
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