|Other Names||Cell death-inducing p53-target protein 1, Cell death involved p53-target, Cell death-inducing protein, LITAF-like protein, Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein, Transmembrane protein I1, CDIP1, C16orf5, CDIP, LITAFL|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||C16orf5, CDIP, LITAFL|
|Function||Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner.|
|Cellular Location||Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Highly expressed in brain. Expressed at lower level in heart, skeletal muscle, kidney, pancreas and liver Weakly or not expressed in placenta and lung|
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Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Brown, L., et al. EMBO J. 26(14):3410-3422(2007)Bhalla, K., et al. J. Hum. Genet. 44(6):383-387(1999)
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