|Other Names||Uncharacterized protein C19orf52, C19orf52|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as the external driving force. Required for the stability of the TIM22 complex and functions in the assembly of the TIMM22 protein into the TIM22 complex. May facilitate cooperation between TIM22 and TOM complexes by interacting with TOMM40.|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side EMBL; AC011442; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC005075; AAH05075.2; -; mRNA EMBL; BC007244; AAH07244.2; -; mRNA EMBL; BC011833; AAH11833.1; -; mRNA CCDS; CCDS12252.1; - RefSeq; NP_612367.1; NM_138358.2 UniGene; Hs.164026; - ProteinModelPortal; Q9BSF4; - BioGrid; 124736; 36 IntAct; Q9BSF4; 10 STRING; 9606.ENSP00000270502; - iPTMnet; Q9BSF4; - PhosphoSitePlus; Q9BSF4; - BioMuta; C19orf52; - DMDM; 74732998; - EPD; Q9BSF4; - MaxQB; Q9BSF4; - PaxDb; Q9BSF4; - PeptideAtlas; Q9BSF4; - PRIDE; Q9BSF4; - ProteomicsDB; 78885; - Ensembl; ENST00000270502; ENSP00000270502; ENSG00000142444 GeneID; 90580; - KEGG; hsa:90580; - UCSC; uc002mqd.3; human CTD; 90580; - EuPathDB; HostDB:ENSG00000142444.6; - GeneCards; TIMM29; - H-InvDB; HIX0014759; - HGNC; HGNC:25152; TIMM29 HPA; HPA041858; - MIM; 617380; gene neXtProt; NX_Q9BSF4; - OpenTargets; ENSG00000142444; - PharmGKB; PA147358399; - eggNOG; KOG4545; Eukaryota eggNOG; ENOG4111K8C; LUCA GeneTree; ENSGT00390000018541; - HOGENOM; HOG000111996; - HOVERGEN; HBG067802; - InParanoid; Q9BSF4; - OMA; YAEACRD; - OrthoDB; EOG091G0ZEJ; - PhylomeDB; Q9BSF4; - TreeFam; TF313304; - GenomeRNAi; 90580; - PRO; PR:Q9BSF4; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000142444; - CleanEx; HS_C19orf52; - ExpressionAtlas; Q9BSF4; baseline and differential Genevisible; Q9BSF4; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB GO; GO:0042721; C:mitochondrial inner membrane protein insertion complex; IDA:UniProtKB GO; GO:0005758; C:mitochondrial intermembrane space; IDA:UniProtKB GO; GO:0045039; P:protein import into mitochondrial inner membrane; IDA:UniProtKB InterPro; IPR019322; TIMM29 PANTHER; PTHR21435; PTHR21435; 1 Pfam; PF10171; Tim29; 1 1: Evidence at protein level; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport; Reference proteome; Transit peptide; Translocation; Transmembrane; Transmembrane helix; Transport TRANSIT 1 31 Mitochondrion. CHAIN 32 260 Mitochondrial import inner membrane translocase subunit Tim29 /FTId=PRO_0000271006 TOPO_DOM 32 59 Mitochondrial matrix TRANSMEM 60 77 Helical. TOPO_DOM 78 260 Mitochondrial intermembrane SEQUENCE 260 AA; 29233 MW; 000324A28C9F2902 CRC64; MAAAALRRFW SRRRAEAGDA VVAKPGVWAR LGSWARALLR DYAEACRDAS AEARARPGRA AVYVGLLGGA AACFTLAPSE GAFEEALLEA SGTLLLLAPA TRNRESEAFV QRLLWLRGRG RLRYVNLGLC SLVYEAPFDA QASLYQARCR YLQPRWTDFP GRVLDVGFVG RWWVLGAWMR DCDINDDEFL HLPAHLRVVG PQQLHSETNE RLFDEKYKPV VLTDDQVDQA LWEEQVLQKE KKDRLALSQA HSLVQAEAPR|
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