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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CAMK2N2 Antibody (N-term) Blocking peptide   

CAMK2N2 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96S95
Clone Names 90904008
Peptide ID 90904008
Additional Information
Gene ID 94032
Other Names Calcium/calmodulin-dependent protein kinase II inhibitor 2, CaM-KII inhibitory protein, CaM-KIIN, CAMK2N2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAMK2N2
Function Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.
Cellular Location Nucleus. Cytoplasm, cytosol. Note=Excluded from nucleus when coexpressed with activated CAMK2.
Tissue Location Expressed in cell lines including hemopoietic cell lines and some tumor cell lines. Highly Expressed in stimulated dendritic cell (DC) and weakly expressed in unstimulated mature and immature DC. Highly expressed in kidney, liver, in cell lines HeLaS3, lymphoblastic leukemia MOLT-4, and Burkitt's lymphoma Raji. Moderately expressed in heart, skeletal muscle, placenta, and chronic myelogenous leukemia K-562 cells Weakly expressed in small intestine, colorectal adenocarcinoma SW480, and lung carcinoma A-549 cells
Research Areas
Citations (0)

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This gene encodes a protein that is highly similar to therat CaM-KII inhibitory protein, an inhibitor ofcalcium/calmodulin-dependent protein kinase II (CAMKII). CAMKIIregulates numerous physiological functions, including neuronalsynaptic plasticity through the phosphorylation ofalpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-typeglutamate (AMPA) receptors. Studies of the similar protein in ratsuggest that this protein may function as a negative regulator ofCaM-KII and may act to inhibit the phosphorylation of AMPAreceptors.


Ma, S., et al. J. Biol. Chem. 284(37):24773-24782(2009)Okabe, T., et al. J. Biol. Chem. 278(11):9920-9927(2003)Zhang, J., et al. Biochem. Biophys. Res. Commun. 285(2):229-234(2001)Chang, B.H., et al. Proc. Natl. Acad. Sci. U.S.A. 95(18):10890-10895(1998)

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$ 99.00
Cat# BP11140a
Availability: In Stock
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