|Other Names||Uncharacterized protein C4orf46, C4orf46|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in the kidney, in epithelial cells in both proximal tubules and distal convoluted tubules EMBL; AK027539; BAG51339.1; -; mRNA EMBL; AK074948; BAG52038.1; -; mRNA EMBL; CH471056; EAX04855.1; -; Genomic_DNA EMBL; BC065017; AAH65017.1; -; mRNA EMBL; BC094775; AAH94775.1; -; mRNA CCDS; CCDS34088.1; - RefSeq; NP_001008394.1; NM_001008393.3 UniGene; Hs.380920; - UniGene; Hs.735449; - ProteinModelPortal; Q504U0; - SMR; Q504U0; - BioGrid; 128401; 7 IntAct; Q504U0; 9 STRING; 9606.ENSP00000368503; - PhosphoSitePlus; Q504U0; - DMDM; 74740214; - EPD; Q504U0; - MaxQB; Q504U0; - PaxDb; Q504U0; - PeptideAtlas; Q504U0; - PRIDE; Q504U0; - ProteomicsDB; 62404; - Ensembl; ENST00000379205; ENSP00000368503; ENSG00000205208 GeneID; 201725; - KEGG; hsa:201725; - UCSC; uc003iqa.4; human CTD; 201725; - EuPathDB; HostDB:ENSG00000205208.4; - GeneCards; C4orf46; - HGNC; HGNC:27320; C4orf46 HPA; HPA047287; - HPA; HPA052670; - MIM; 616210; gene neXtProt; NX_Q504U0; - OpenTargets; ENSG00000205208; - PharmGKB; PA162379968; - eggNOG; ENOG410J52F; Eukaryota eggNOG; ENOG4111AB8; LUCA GeneTree; ENSGT00390000003125; - HOGENOM; HOG000054226; - HOVERGEN; HBG096306; - InParanoid; Q504U0; - OMA; MANPEGL; - OrthoDB; EOG091G14KU; - PhylomeDB; Q504U0; - TreeFam; TF338687; - ChiTaRS; C4orf46; human GenomeRNAi; 201725; - PRO; PR:Q504U0; - Proteomes; UP000005640; Chromosome 4 Bgee; ENSG00000205208; - CleanEx; HS_C4orf46; - ExpressionAtlas; Q504U0; baseline and differential Genevisible; Q504U0; HS GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell InterPro; IPR031457; RCDG1 PANTHER; PTHR31641; PTHR31641; 1 Pfam; PF15725; RCDG1; 1 1: Evidence at protein level; Complete proteome; Cytoplasm; Reference proteome CHAIN 1 113 Renal cancer differentiation gene 1 protein /FTId=PRO_0000335689 SEQUENCE 113 AA; 11899 MW; 6FE4325ED2C2CAB2 CRC64; MADPEELQVS SPPPPPPSSP SSSDASAASS PGGPVSLGWP VPSRSSGPTV DQLEEVELQI GDAAFSLTKL LEATSAVSAQ VEELAFKCTE NARFLKTWRD LLKEGYDSLK PDD|
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Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity).
Illig, T., et al. Nat. Genet. 42(2):137-141(2010)
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